何梦

笔者:bck体育网页版 发布时间:2019.01.16 15:27
  
  姓名:何梦
  性别:女
  出生年月:1986年12月

  学历/学位:博士学位

  职称:副教授

  联系电话:15347231527

  Email:menghe@whut.edu.cn.

  教育经历 

  2016.07-至今 bck体育网页版制药工程系 副教授

  2010.09-2016.07澳大利亚伍伦贡大学 药理学 获博士学位

  2009.09-2010.09 西南大学 微生物与生化药学 硕士肄业(提前攻博)

  2005.09-2009.06西南大学 制药工程 获学士学位

  研究经历

  2016-现在:神经退行性疾病的药物开发及治疗机制研究,抗精神病药物所致代谢综合征的机制研究及药物干预

  2010-2016:抗精神病药物所致代谢综合征的机制研究及药物干预

  2009-2010:三峡库区土壤真菌次级代谢产物抗肿瘤活性及作用机制研究

  研究领域 

  药效学、药理学、神经病理学、神经内分泌

  代表性论文与专著 

  1. 期刊论文 

  1. Guanbin Gaoa, Rui Chen, Meng He (共一作), Jing Li Jing Li, Liyun Wang, Taolei Sun*. Gold nanoclusters for Parkinson's disease treatment. 2019,Biomaterials 194 (2019) 36–46. 国际A 区, IF=8.806,SCI收录

  2. Meng He, Qingsheng Zhang, Chao Deng, Tiantian Jin, Xueqin Song, Hongqin Wang, Xu-Feng Huang*, Time-dependent e?ects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity, Psychoneuroendocrinology,2017, 85,190-199. 国际A 区,IF=4.731,SCI收录

  3. Meng He, Qingsheng Zhang, Chao Deng, Hongqin Wang, Xu-Feng Huang*, Olanzapine-activated AMP-activated protein kinase signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats, Endocrinology, 2014, 155 (12):4895-4904. 国际B 区,IF=3.931,SCI收录

  4. Meng He, Qingsheng Zhang, Chao Deng, Hongqin Wang, Jiamei Lian, Xu-Feng Huang*, Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats, Psychoneuroendocrinology, 2014, 42, 153-164. 国际A 区,IF=4.731,SCI收录

  5. Meng He, Chao Deng, Xu-Feng Huang*, The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain, CNS Drugs, 2013, 27 (6), 423-434. 国际A 区,IF=4.206,SCI收录

  6. Zhang Qingsheng, Meng He, Chao Deng, Hongqin Wang, Xu-Feng Huang*, Effects of olanzapine on elevation of macrophage infiltration and pro-inflammation cytokine expressions in female rats, Journal of psychopharmacology, 2014, 28(12):1161-1169. 国际A 区,IF=4.738, SCI收录

  7. Zhang Qingsheng, Meng He, Chao Deng, Hongqin Wang, Jiamei Lian, Xu-Feng Huang*, Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats, The international journal of neuropsychopharmacology, 2014, 17, 807-818. 国际A 区,IF=3.981,SCI收录

  8. Zhang Qingsheng, Jiamei Lian, Meng He, Chao Deng, Hongqin Wang, Xu-Feng Huang*, Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats, Progress in neuro-psychopharmacology & biological psychiatry, 2014, 51, 172-180. 国际A 区,IF=3.247,SCI收录

  9. Jiamei Lian, MichaelDe Santis, Meng He, Chao Deng*, Risperidone-induced weight gain and reduced locomotor activity in juvenile female rats: The role of hsitaminergic and NPY pathways, Pharmacological research, 2015, May-Jun; 20-26. 国际A 区,IF=4.897,SCI收录

  10. Yanming Wan, Ying Bu, Jiaming Liu, Jia Yang, Weiquan Cai, Yihua Yin*, Wenjin Xu,  Peihu Xu, Jingli Zhang* and Meng He. pH and reduction-activated polymeric prodrug nanoparticles based on a 6-thioguanine-dialdehyde sodium alginate conjugate for enhanced intracellular drug release in leukemia, Polymer Chemistry, 2018, 9, 3425. 国际A 区, IF=4.927,SCI收录

  2、会议论文 

  1. He, M., Wang, H.Q., Han, M., Deng, C. and Huang X.F*. Acute olanzapine treatment blocks the histamine H1 receptors leading to activated AMPK signaling in the hypothalamic arcuate nucleus and brainstem dorsal vagal complex, 34th Australian Neuroscience Society Annual meeting, Adelaide,Australia, 2014.01.28- 01.31.

  2. He, M. , Zhang, Q., Wang, H.Q., Deng, C. and Huang, X.F*.  Central administration of histamine H1 receptor agonist, FMPH, blocks olanzapine-induced activation of AMPK-CPT1 signaling in the dorsal vagal complex in rats, Australian Neuroscience Society 33rd Annual Meeting, Melbourne, Australia, 2013.03.03-03.06.

  3. He M., Zhang, Q., Wang, H.Q., Lian, J., Deng, C. and Huang, X.F*. Olanzapine treatment and time-dependent changes of hypothalamic AMPK-ACC-CPT1 signaling, food intake and body weight in rats, Australian Neuroscience Society 32nd Annual Meeting, Gold Cost, Australia, 2012.01.29-02.01.

  4. Zhang, Q., He, M., Wang, H., Lian, J., Deng, C. and Huang, X.F*, Brown Adipose Tissue Thermogenesis Is Time-Dependently Downregulated by Olanzapine in Rats, Proceedings of the 31st Annual Scientific Meeting of the Obesity Society, Atlanta, GA, USA, 2013.10.31-11.02

  5. Zhang, Q., He, M., Wang, H., Lian, J., Deng, C. and Huang, X.F*, Time-dependent ghrelinergic signaling and hyperphagia induced by olanzapine, Australian Neuroscience Society 33rd Annual Meeting, Melbourne, Australia, 2013.03.03-03.06.

  6. Zhang, Q., He, M., Wang, H., Lian, J., Deng, C. and Huang, X.F*, Time-dependant alterations of hypothalamic energy regulatory network by olanzapine in rats, Australian Neuroscience Society 32nd Annual Meeting, Gold Cost, Australia, 2012.01.29-02.01.

  

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