张方林

笔者:bck体育网页版 发布时间:2019.01.17 10:08

   

  姓名:张方林 

  性别: 

  出生年月: 19777 

  学位:博士 

  职称:教授 

  联系电话:15972213793 

  Emailhyvzfl@gmail.com 

    

  教育、工作经历: 

  1995.09-1999.06 华中科技大学化学BCKBET             学士 

  1999.07-2002.08 中国乐凯胶片集团公司研究院 

  2002.09-2008.06 华中科技大学化学BCKBET             理学博士 

  2008.07-2011.07 华中科技大学生命科学与技术BCKBET        博士后 

  2011.08-目前   bck体育网页版      副教授 

  研究领域: 

     不对称催化、手性药物合成、具有生理活性化合物的全合成。 

  教学、科研概况 

     坚信君子应务本,对待工作认真负责、爱岗敬业,不断提高业务能力,与同事关系融洽。讲授本科课程:药物合成化学、制药工艺学等,受到了督导专家和学生的一致好评;指导国家大学生创新本科生项目1项。 

  近年主持的主要科研项目 

     不对称有机催化氧杂Michael 加成引发的多组分串联反应。国家自然科学基金青年基金2010.01~2012.12 主持。 

  近年代表性论文与专利: 

  [1] Jiaxing Hu, Zhihong Deng, Xueqiong Zhang, Fanglin Zhang* and Hua Zheng*. Synthesis of benzofuro[2,3-c]pyridines via a one-pot three-component reaction. Organic & Biomolecular Chemistry, 2014, 12, 4885-4889.

  [2] Qingcui Li, Wengang Xu, Jiaxing Hu, Xiaoqing Chen, Fanglin Zhang*, Hua Zheng*. TfOH catalyzed synthesis of 9-arylfluorenes via tandem reaction under warm and efficient conditions. RSC Advances 2014, 4, 27722-27725.

  [3] Jiaxing Hu, Dandan Liu, Wengang Xu, Fanglin Zhang*, Hua Zheng*. One-pot Reaction for the Concise Synthesis of Spiro[benzofuran-2,2'-naphthalen]-1'-one Derivatives. Tetrahedron 2014, accept.

  [4] MoHui Wei , YiRong Zhou, LiangHu Gu , Fan Luo*, FangLin Zhang*. Asymmetric organocatalytic Michael-Hemiacetalization reaction: access to chiral spiro cis-δ-lactones by in situ oxidation of spiro δ-lactols. Tetrahedron Lett., 2013, 54, 2546-2548.

  [5] Guoxi Xiong, Mohui Wei, Yirong Zhou, Yungui Li, Fanglin Zhang,* Yuefa Gong*. A Multicomponent Reaction between α-Substituted Acroleins, Nitroalkanes and Paraformaldehyde: Efficient Construction of Nitro δ-Lactol. Synthesis, 2011, 3439-3446.

  [6] Yirong Zhou, Junfang Dong, Fanglin Zhang,* and Yuefa Gong*. Synthesis of C1-Symmetric Chiral Secondary Diamines and Their Applications in the Asymmetric Copper(II)-Catalyzed Henry (Nitroaldol) Reactions. J. Org. Chem. 2011, 76, 588-600

  [7] Fanglin Zhang, MoHui Wei, JunFang Dong, YiRong Zhou, DengFu Lu, YueFa Gong and XiangLiang Yang. A Recyclable Organocascade Reaction System: Stereoselective Precipitation of Optically Pure cis-d-Lactols with Quaternary Stereocenters during the Michael-Hemiacetalization Reaction. Adv. Synth. Catal. 2010, 352, 2875-2880

  [8] Fanglin Zhang, AiWen Xu, YueFa Gong, MoHui Wei, XiangLiang Yang. Asymmetric Organocatalytic Four-Component Quadruple Domino Reaction Initiated by Oxa-Michael Addition of Alcohols to Acrolein. Chem. Eur. J. 2009, 15, 6815-6818.

  [9] Fanglin Zhang, Yiyuan Peng and Yuefa Gong. Asymmetric Synthesis of Bicyclic Piperidines via L-Proline Catalyzed Aldol Reaction of 3-Phthalimidopropanal. Chirality 2008, 20, 806-811.

  [10] Fanglin Zhang, Yiyuan Peng, Saihu Liao and Yuefa Gong. Pyrrolidine as an Efficient Organocatalyst for Direct Aldol Reaction of Trifluoroacetaldehyde Ethyl Hemiacetal with Ketones Tetrahedron 2007, 63, 4636–4641.

  [11] Fanglin Zhang, Ning Su and Yuefa Gong. Highly Selective Catalytic Cross Aldol Reactions of Chloral with Aliphatic Aldehydes. Synlett. 2006, 1703-1706. 

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