崔晓峰

笔者:bck体育网页版 发布时间:2019.01.21 10:00

   

  

   姓名:崔晓峰    

  性别:    

  出生年月:  

  学位:博士    

  职称:湖北省楚天学者特聘教授、bck体育网页版教授、博士生导师、德国慕尼黑工业大学讲座教授、美国伦斯勒理工大学兼职教授 

  联系电话:      

  Emailxfcui@whut.edu.cn xfc.cui@gmail.com 

    

  教育经历: 

  2004/5-2008/12 美国克莱姆森大学生物医学工程系,博士 

  2001/8-2004/5 美国克莱姆森大学材料科学与工程系,硕士 

  1994/09-1998/07 华东理工大学生化工程系,学士 

  工作经历: 

  2015-至今 德国慕尼黑工业大学,讲座教授 

  2014-至今 bck体育网页版,教授、博士生导师 

  2013-2018 美国伦斯勒理工大学生物技术交叉学科研究中心,兼职教授 

  2013-2014 美国斯特摩根公司,首席科学家,研发总监 

  2010-2013 美国斯克里普斯研究所,资深科学家 

  2009-2010 美国斯克利普斯研究所,博士后研究员 

  研究领域: 

  生物材料;生物3D打印;高通量药敏检测和药物筛选;干细胞研究和应用;关节软骨、半月板、骨骼与肌肉的组织工程;生物传感器;器官芯片。 

  招收研究生博士生方向:生物技术、药学、生物材料、生物医学工程、医学、高分子化学等 

  课题组长期招收博士后、博士生、研究生 

主要科研项目: 

1. 国家自然科学基金青年科学基金项目:生物打印复合材料和干细胞在半月板组织工程中的应用和机理研究,01/01/2019-12/31/2021

2. 湖北省科学技术厅一般面上项目:运用生物3D打印技术构建半月板组织工程产物,03/2018-03/2020

3. 基于3D打印的毛囊化皮肤模型的构建和应用基础研究,中央高校基本科研基础学科重点项目,01/2017-12/2018

4. 生物3D打印平台的建设,企业委托,01/2017-12/2018

5. bck官网第二轮“15551人才工程”青年拔尖人才第一层次,12/2016-11/2021

6. 楚天学者特聘教授科研平台建设基金,06/2014-06/2019

7. bck官网2017ESI面上项目-材料科学,01/2017-12/2017

8. 半月板增材组织制造的研究,中央高校基本科研基础学科重点项目,01/2015-12/2016

代表性论文与专利:

作为世界上最早开始研究生物3D打印和细胞生物打印的专家学者,崔教授曾成功打印出世界上首例具有生理功能的人毛细血管网,该工作发表在生物材料领域顶级期刊Biomaterials上。在美国顶级生物医学研究单位斯克利普斯研究所打印出世界首例达到人关节软骨各项指标的生物活性软骨组织,该工作荣获第十届国际软骨修复学会最佳论文奖(500篇论文中的第一名)和美国斯克利普斯研究所杰出贡献奖。崔教授亦曾先后获得国际骨科研究学会著名研究员奖、国际软骨修复学会优秀论文奖、美国生物材料学会杰出贡献奖、美国国家纺织中心主席奖、美国政府杰出海外人士、入选美国名人录等荣誉。在生物3D打印、智能生物材料、干细胞研究和应用、血管构建、生物反应器、高通量药物筛选、关节软骨、半月板、骨骼和肌肉的组织工程等研究领域发表高水平学术期刊与会议论文数十篇,同行论文引用超过3500次以上,H-index 21。崔教授现在担任欧盟基金会评委、澳大利亚国家基金理事会评委、法国牙科研究学会基金评委、中国教育部长江学者评审专家、中国工程院“中国3D打印材料及应用发展战略研究”特聘专家、五十余种国际学术期刊的审稿专家。曾受邀亲自参加美国探索频道关于生物3D打印专题节目的录制拍摄,接受已有近40年历史的美国老牌科学杂志GEN的专访,其研究工作被美国CNNFOX等国家新闻网广泛报道。并受邀在国际学术会议和世界著名大学(包括普林斯顿大学、杜克大学、德州大学MD安德森癌症医学中心、加州大学等)做学术报告30余次。

1. Ming Li, Chuang Ma, Xiong Liu, Jun Su, Xiaofeng Cui, Yunbin He. Synthesis of a 2D phosphorus material in a MOF-based 2D nano-reactor. Chemical Science, 2018 June; 9(27):5912-5918. doi: 10.1039/c8sc01439f (IF: 9.063, 中科院SCI 1)

2. Riho Kurata#, Asuka Kumagai#, Xiaofeng Cui#, Masamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki, Yoshimasa Tanaka, Tomo Yonezawa. Establishment of novel reporter cells stably maintaining transcription factor-driven human secreted alkaline phosphatase expression. Current Pharmaceutical Biotechnology, 2018; 19(3):224-231. doi: 10.2174/1389201019666180418093334 (共同一作,IF: 1.819SCI)

3. Guifang Gao, Ying Huang, Arndt F. Schilling, Karen Hubbell, Xiaofeng Cui*. Organ Bioprinting: Are We There Yet? Advanced Healthcare Materials, 2018 Jan; 7(1). doi: 10.1002/adhm.201701018 (通讯作者,IF: 5.609, 中科院SCI 1)

4. Xiaofei Zhang, Jun Li, Pengxiang Ye, Guifang Gao, Xiaofeng Cui*. Coculture of mesenchymal stem cells and endothelial cells enhances host tissue integration and epidermis maturation through AKT activation in GelMA hydrogel-based skin model. Acta Biomaterialia, 2017 Sep; 59:317-326. doi: 10.1016/j.actbio.2017.07.001 (通讯作者,IF: 6.383, 中科院SCI 1)

5. Ying Huang, Xiao-Fei Zhang, Guifang Gao, Tomo Yonezawa, Xiaofeng Cui*. 3D Bioprinting and the Applications in Tissue Engineering. Biotechnology Journal, 2017 Aug; 12(8). doi: 10.1002/biot.201600734 (通讯作者,IF: 3.507, JCR 1)

6. Xiaofei Zhang, Rongfu Tu, Keke Li, Pengxiang Ye, Xiaofeng Cui*. Tumor Suppressor PRPRJ is a Target of miR-155 in Colorectal Cancer. Journal of Cellular Biochemistry, 2017 Oct; 118(10):3391-3400. doi: 10.1002/jcb.25995 (通讯作者,IF: 2.959, 中科院SCI 2)

7. Xiaofei Zhang, Xiaofeng Cui*. Connexin 43: Key Roles in the Skin. Biomedical Reports, 2017 Jun; 6(6):605-611. doi: 10.3892/br.2017.903 (通讯作者)

8. Guifang Gao, Xiao-Fei Zhang, Karen Hubbell, Xiaofeng Cui*. NR2F2 Regulates Chondrogenesis of Human Mesenchymal Stem Cells in Bioprinted Cartilage. Biotechnology and Bioengineering, 2017 Jan; 114(1):208-216, 2017. doi: 10.1002/bit.26042 (通讯作者,IF: 3.952, 中科院SCI 1)

9. Xiaofeng Cui, Yao Wei Lu, Vivian Lee, Diana Kim, Taylor Dorsey, Qingjie Wang, Young Lee, Peter Vincent, John Schwarz, Guohao Dai. Venous Endothelial Marker COUP-TFII Regulates the Distinct Pathologic Potentials of Adult Arteries and Veins. Scientific Reports, 2015 Nov; 5:16193. doi: 10.1038/srep16193 (IF: 4.122, SCI Nature子刊)

10. Guifang Gao, Xiaofeng Cui*. Three-dimensional Bioprinting in Tissue Engineering and Regenerative Medicine. Biotechnology Letters, 2016 Feb; 38(2):203-211. doi:10.1007/s10529-015-1975-1 (通讯作者,IF: 1.846, SCI)

11. Guifang Gao, Arndt F. Schilling, Karen Hubbell, Tomo Yonezawa, Danh Truong, Yi Hong, Guohao Dai, Xiaofeng Cui*. Improved Properties of Bone and Cartilage Tissue from 3D Inkjet-bioprinted Human Mesenchymal Stem Cells by Simultaneous Deposition and Photocrosslinking in PEG-GelMA. Biotechnology Letters, 2015 Nov; 37(11):2349-2355. doi: 10.1007/s10529-015-1921-2 (通讯作者,IF: 1.846, SCI)

12. Guifang Gao, Tomo Yonezawa, Karen Hubbell, Guohao Dai, Xiaofeng Cui*. Inkjet-bioprinted acrylated peptides and PEG hydrogel with human mesenchymal stem cells promote robust bone and cartilage formation with minimal printhead clogging. Biotechnology Journal, 2015 Oct; 10(10):1568-1577. doi: 10.1002/biot.201400635 (通讯作者,IF: 3.507, JCR 1)

13. Guifang Gao, Arndt F. Schilling, Tomo Yonezawa, Jiang Wang, Guohao Dai, Xiaofeng Cui*. Bioactive Nanoparticles Stimulate Bone Tissue Formation in Bioprinted Three-Dimensional Scaffold and Human Mesenchymal Stem Cells. Biotechnology Journal, 2014 Oct; 9(10):1304-1311. doi: 10.1002/biot.201400305 (通讯作者,IF: 3.507, JCR 1)

14. Xiaofeng Cui*, Guifang Gao, Tomo Yonezawa, Guohao Dai. Human Cartilage Tissue Fabrication Using Three-Dimensional Inkjet Printing Technology. JOVE-Journal of Visualized Experiments, 2014 Jun; (88), e51294. doi: 10.3791/51294 (IF: 1.184, SCI)

15. Riho Kurata, Xiaofeng Cui, Roh Saug-gun, Tomo Yonezawa. Supplementation of Long-Chain Fatty Acids with lactating Mammary Glands and Beef Cow has Potential Benefits. Advances in Plants and Agriculture Research, 2015. doi: 10.15406/apar.2015.02.00063

16. Tomo Yonezawa T, Riho Kurata, Atsushi Tajima, Xiaofeng Cui, Hiroki Maruta, Hirofumi Nakaoka, Keiichi Nakajima, Hidetoshi Inoko. Comparative Proteomics and Network Analysis Identify PKC Epsilon Underlying Long-Chain Fatty Acid Signaling. Journal of Proteomics and Bioinformatics, 2014; 7(11):340-346 (IF: 2.56)

17. Tomo Yonezawa, Riho Kurata, Kaori Yoshida, Masanori A. Murayama, Xiaofeng Cui, Akihiko Hasegawa. Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics. Current Medicinal Chemistry, 2013; 20(31):3855-3871. doi: 10.2174/09298673113209990168 (IF: 3.469, SCI A )

18. Xiaofeng Cui*, Guifang Gao, Yongjun Qiu. Accelerated Myotube Formation Using Bioprinting Technology for Biosensor Applications. Biotechnology Letters, 2013 Mar; 35(3):315-321. doi:10.1007/s10529-012-1087-0 (IF: 1.846, SCI)

19. Xiaofeng Cui, Kurt Breitenkamp, Martin Lotz, Darryl DLima. Synergistic Action of FGF-2 and TGF-β1 Enhances Bioprinted Human Neocartilage Formation. Biotechnology and Bioengineering, 2012 Sep; 109(9):2357-2368. doi: 10.1002/bit.24488 (IF: 3.952, SCI 1)

20. Xiaofeng Cui*, Akihiko Hasegawa, Martin Lotz, Darryl D’Lima. Structured 3D Co-culture of Mesenchymal Stem Cells with Meniscus Cells Promotes Meniscal Phenotype without Hypertrophy. Biotechnology and Bioengineering, 2012 Sep; 109(9):2369-2380. doi: 10.1002/bit.24495 (IF: 3.952, SCI 1)

21. Xiaofeng Cui*, Thomas Boland, Darryl D. D’Lima, Martin K. Lotz. Thermal Inkjet Printing in Tissue Engineering and Regenerative Medicine. Recent Patents on Drug Delivery and Formulation, 2012 Aug; 6(2):149-155. doi:10.2174/187221112800672949 (IF: 2.46)

22. Xiaofeng Cui, Kurt Breitenkamp, M.G. Finn, Martin Lotz, Darryl D. D’Lima. Direct Human Cartilage Repair Using 3D Bioprinting Technology. Tissue Engineering Part A, 2012 June; 18(11-12):1304-1312. doi: 10.1089/ten.TEA.2011.0543 (Reported on Science) (IF: 4.448, SCI A)

23. Xiaofeng Cui*, Michael Ellison. Effects of Biodiesel Waste Glycerol on the Growth Characteristics of Pichia pastoris Genetically Modified to Produce Spidroin. International Journal of ChemTech Research, 2012; 4(2):713-9.

24. Xiaofeng Cui*, Kurt Breitenkamp, M.G. Finn, Martin Lotz, Clifford W. Colwell. Direct Human Cartilage Repair Using Thermal Inkjet Printing Technology. Osteoarthritis and Cartilage, 2011 Sep; 19:S47-48. (IF: 5.454, SCI 1)

25. Xiaofeng Cui*, Delphine Dean, Zaverio M. Ruggeri, Thomas Boland. Cell Damage Evaluation of Thermal Inkjet Printed Chinese Hamster Ovary Cells. Biotechnology and Bioengineering, 2010 Aug; 106(6):963-969. doi: 10.1002/bit.22762 (IF: 3.952, SCI 1)

26. Bas de Laat, Xiaofeng Cui, Jennifer Nagrampa-Orje, Mariko Yabe, James R Roberts, Zaverio M Ruggeri, Biomechanical Properties of the Glycoprotein Ib-von Willebrand Factor Interaction under Flow. Circulation, 2009 Nov; 120(18):S1169. (IF: 18.880, SCI 1)

27. Xiaofeng Cui, Thomas Boland. Human Microvasculature Fabrication Using Thermal Inkjet Printing Technology. Biomaterials, 2009 Oct; 30(31):6221-6227. doi: 10.1016/j.biomaterials (IF: 8.806, SCI 1)

28. Changhong Zhang, Kejia Zhao, Tianyi Hu, Xiaofeng Cui, Nathan Brown, Thomas Boland. Loading Dependent Swelling and Release Properties of Novel Biodegradable, Elastic and Environmental Stimuli-sensitive Polyurethanes, Journal of Controlled Release, 2008 Oct; 131(2):128-136. doi: 10.1016/j.jconrel.2008.07.026 (IF: 7.877, SCI 1)

29. Xiaofeng Cui, Thomas Boland, Simultaneous Deposition of Human Microvascular Endothelial Cells and Biomaterials for Human Microvasculature Fabrication Using Inkjet Printing, NIP24/digital Fabrication 2008: 24th International Conference on Digital Printing Technologies, Technical Program and Proceedings, 2008; 24:480-483.

30. Sandra Deitch, Catherine Kunkle, Xiaofeng Cui, Thomas Boland, Delphine Dean. Collagen Matrix Alignment Using Inkjet Printer Technology, Materials Research Society Symposium Proceedings, 2008; 1094:DD07-16

31. Nripen Singh, Xiaofeng Cui, Thomas Boland, Scott M. Husson. The Role of Independently Variable Grafting Density and Layer Thickness of Polymer Nanolayers on Peptide Adsorption and Cell Adhesion, Biomaterials, 2007 Feb; 28(5):763-771. doi: 10.1016/j.biomaterials.2006.09036 (IF: 8.806, SCI 1)

32. Thomas Boland, Xiaofeng Cui, Aditya Chaubey, Timothy C. Burg, Richard E. Groff, Karen J. L. Burg, Precision Printing of Cells and Biomaterials onto 3D Matrices, Proceedings of the ASME International Conference on Manufacturing Science and Engineering, 2007; MSEC2007 (31023):77-81

33. Thomas Boland, Xiaofeng Cui, Michael Aho, Catalin Baicu, Michael Zile. Image Based Printing of Structured Biomaterials for Realizing Complex 3D Cardiovascular Constructs, Journal of Imaging Science and Technology, 2006; 2:86-88 (SCI)

34. Thomas Boland, Tao Xu, Brook Damon, Xiaofeng Cui. Application of Inkjet Printing to Tissue Engineering, Biotechnology Journal, 2006 Sep; 1(9):910-917. doi:10.1002/biot.200600081  (IF: 3.446, JCR 1)

35. Tao Xu, Cassie A. Gregory, Peter Molnar, Xiaofeng Cui, Sahil Jalota, Sarit B. Bhaduri, Thomas Boland. Viability and Electrophysiology of Neural Cell Structures Generated by the Inkjet Printing Method, Biomaterials, 2006 Jul; 27(19):3580-3588. doi:10.1016/i.biomaterials.2006.01.048  (IF: 8.557, SCI 1)

36. Nripen Singh, Scott M. Husson, Xiaofeng Cui, Thomas Boland. Polymer Brush Layers with Variation of Grafting Density for Peptide Adsorption and Cell Adhesion Studies, Abstracts of Papers of the American Chemical Society, 2006; 231:418-PMSE (SCI)

37. Guifang Gao, Karen Hubbell, Arndt F. Schilling, Guohao Dai, Xiaofeng Cui*. Bioprinting Cartilage Tissue from Mesenchymal Stem Cells and PEG Hydrogel. Methods in Molecular Biology, 1612:391-398. doi: 10.1007/978-1-4939-7021-6_28. Editor: Zuzana Koledova. Springer. 2017

38. Xiao-Fei Zhang, Ying Huang, Guifang Gao, Xiaofeng Cui*. Current Progress in Bioprinting. Advances in Biomaterials for Biomedical Applications. Editors: Anuj Tripathi and Jose Savio Melo. Springer Science+Business Media Singapore Pte Ltd. 2016

39. Xiaofeng Cui*. Three-dimensional Bioprinting in Regenerative Medicine. Stem Cell Biology and Regenerative Medicine. Series Editor: Kursad Turksen. Springer. 2015

40. Xiaofeng Cui*. Synthetic and Natural Polymers as Bioink for Printed Biomaterials. Printed Biomaterials. Editors: Lee YS, Narayan R, Boland T. Springer. 2010

  学术奖励及荣誉 

  2016国际软骨修复学会优秀论文奖 

  2014湖北省楚天学者特聘教授 

  2014美国名人录 

  2012国际软骨修复学会最佳论文奖(国际大会最高奖项,500篇论文中唯一获奖者) 

  2012美国斯克利普斯研究院杰出贡献奖 

  2012国际软骨修复学会世界大会奖学金 

  2012国际骨科研究学会著名研究员奖 

  2012美国政府杰出海外人士 

  2009国际生物材料学会杰出贡献奖 

  2008美国真空学会Dorothy M. & Earl S. Hoffman 

  2005美国国家纺织中心主席奖 

  主要学术兼职: 

  美国国立卫生总署(NIH)、美国国家科学基金会(NSF)、欧盟委员会 (European Commission)、澳大利亚国家基金理事会(NHMRC)、法国牙科研究学会(IFRO)基金评委;中国教育部长江学者评审专家;中国工程院“中国3D打印材料及应用发展战略研究”特聘专家

  学术期刊评审专家: 

  ACS Applied Materials & InterfacesACS Biomaterials Science & EngineeringActa BiomaterialiaAdvanced BiosystemsAdvanced Functional MaterialsAdvanced Healthcare MaterialsAdvanced MaterialsAdvanced TherapeuticsAdvances in Materials Science and EngineeringAnnals of Biomedical EngineeringApplied Materials TodayBiofabricationBiomaterialsBiomedical MaterialsBioprintingBiotechnology and BioengineeringBiotechnology JournalBiotechnology ProgressComposites Part BCurrent Medicinal ChemistryCurrent Pharmaceutical BiotechnologyDrug Discovery TodayEuropean Medical JournalFuture MedicineInternational Journal of Heat and Mass TransferLife SciencesJournal of Biomedical Materials ResearchJournal of Cell Science & TherapyJournal of Medical Case ReportsJournal of Nutrition & Food SciencesJournal of Regenerative MedicineJournal of the American Pharmacists AssociationJournal of the Mechanical Behavior of Biomedical MaterialsJournal of Tissue Science and EngineeringJournal of Trauma and TreatmentJournal of Stem Cell Research & TherapyJournal of Visualized ExperimentsMaterials & DesignOncology LettersRegenerative MedicineScientific ReportsSmallStem Cells InternationalTissue EngineeringTrends in Biotechnology

 

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